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Vol. 33. Num. 2.April - June 2013
Pages 49-110
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Vol. 33. Num. 2.April - June 2013
Pages 49-110
Original article
DOI: 10.1016/j.jcol.2013.02.004
Open Access
Incidence and epidemiological features of synchronous and metachronous colorectal cancer
Incidência e perfil epidemiológico do câncer colorretal sincrônico e metacrônico
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Eduardo Brambillaa,
Corresponding author
brambilla.procto@gmail.com

Corresponding author.
, Augusto Cardoso Sgarionib, Guilherme Fingera, Guilherme Sartoria, Maicon Joel Cimarostia
a Universidade de Caxias do Sul, Caxias do Sul, RS, Brazil
b Department of General Surgery, Hospital Geral de Caxias do Sul, Caxias do Sul, RS, Brazil
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Under a Creative Commons license
Article information
Abstract
Introduction

patients with sporadic colorectal cancer or cases associated with syndromes are at risk of having synchronous or metachronous cancer. Although it is an important subject, Brazilian data on the subject are scarce.

Objective

to evaluate the incidence and epidemiological features in patients with synchro- nous and metachronous colorectal cancer in a reference service of proctology in the Rio Grande do Sul.

Methods

cross-sectional observational study, performed between January and July 2012, analyzing all patients admitted in the service that met the inclusion criteria. A retrospective review of records was performed, noting demographic variables, comorbidi- ties and tumor-related variables.

Results

150 records were analyzed, of which 53.3% were males and mean age was 63 (± 13.01) years old. The most frequently found tumor location was the sigmoid colon and high rectum (50.67%), followed by the lower rectum (36%). Adenocarcinomas were the most prevalent histological subtype (88%), followed by epidermoid tumors (1.33%). Hereditary syndromes were identified in five patients (3.33%), with four being Familial adenomatous polyposis (FAP) and one hereditary nonpolyposis colorectal cancer (HNPCC). Among the an- alyzed patients, four (2.67%) had synchronous and one (0.67%) had metachronous cancer.

Conclusion

the incidence of synchronous and metachronous colorectal cancer was, respectively, 2.67% and 0.67%, results that corroborate those reported in international literature.

Keywords:
Colonic neoplasms
Colorectal neoplasms
Colorectal surgery
Epidemiology
Surgery
Resumo
Introdução

pacientes com diagnóstico de câncer colorretal esporádico ou associado a sín- dromes correm risco de apresentar lesões sincrônicas ou metacrônicas. Embora seja rele- vante, há escassez de informações sobre o tema na literatura nacional.

Objetivo

avaliar a incidência e o perfil epidemiológico dos pacientes com tumor colorretal sincrônico e metacrônico em um serviço de referência em proctologia do Rio Grande do Sul.

Método

estudo observacional transversal, realizado entre janeiro e julho de 2012, avaliando-se pacientes atendidos no serviço que preencheram os critérios de inclusão. Revisaram-se os prontuários, registrando-se variáveis demográficas, comorbidades e variáveis relacionadas ao tumor.

Resultados

analisaram-se 150 prontuários, sendo 53,3% do sexo masculino com média de idade de 63 (+13,01) anos. A topografia mais incidente foi cólon sigmoide e reto alto (50,67%) seguido do reto baixo (36%). O adenocarcinoma foi o subtipo histológico mais prevalente (88%) seguido pelo epidermoide (1,33%). Síndromes hereditárias foram identificadas em cinco pacientes (3,33%), sendo quatro com polipose adenomatosa familiar e um paciente com câncer colorretal hereditário não polipose. Dos 150 pacientes, quatro (2,67%) apresen- taram neoplasia sincrônica e um (0,67%) lesão metacrônica. Conclusão: a incidência de tu- mor colorretal sincrônico e metacrônico na população avaliada foi, respectivamente, 2,67% e 0,67%, resultados que corroboram achados da literatura estrangeira.

Palavras-chave:
Neoplasias de cólon
Neoplasias colorretais
Cirurgia colorretal
Epidemiologia
Cirurgia
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Copyright © 2013. Sociedade Brasileira de Coloproctologia
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Journal of Coloproctology

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